ggPMX - 'ggplot2' Based Tool to Facilitate Diagnostic Plots for NLME
Models
At Novartis, we aimed at standardizing the set of
diagnostic plots used for modeling activities in order to
reduce the overall effort required for generating such plots.
For this, we developed a guidance that proposes an adequate set
of diagnostics and a toolbox, called 'ggPMX' to execute them.
'ggPMX' is a toolbox that can generate all diagnostic plots at
a quality sufficient for publication and submissions using few
lines of code. This package focuses on plots recommended by
ISoP <doi:10.1002/psp4.12161>. While not required, you can
get/install the 'R' 'lixoftConnectors' package in the 'Monolix'
installation, as described at the following url
<https://monolix.lixoft.com/monolix-api/lixoftconnectors_installation/>.
When 'lixoftConnectors' is available, 'R' can use 'Monolix'
directly to create the required Chart Data instead of exporting
it from the 'Monolix' gui.